Back to search

Peptide record

TPDB10402

Antibacterial Antifungal Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10402
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FWGALAKGALKLIPSLVSSFTKKD
Physicochemical Analysis
C123H197N29O31
RNCEQHMY
LK
2578.09
10.55
4
1
12
+3
-0.91
0.392
105.83
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
213.34
4
Residue Composition
number
3
A
0
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
1
I
4
L
4
K
0
M
2
F
1
P
3
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 4 K: 4 M: 0 F: 2 P: 1 S: 3 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
24
C123H197N29O31
2578.09
10.55
+3
-0.91
0.392
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
415.8-30 µM

Target

M. luteus AB2010179

Source & Reference

NA

Other

Active against Gram+ B. megaterium AB 90008 M. luteus AB2010179 (MIC 415.8-30 uM) S. aureus AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 1
Evidence 2 Activity

Activity

MIC
Antibacterial
5.6 µM

Target

Staphylococcus aureus AB 94004

Source & Reference

NA

Other

Active against Gram+ B. megaterium AB 90008 M. luteus AB2010179 (MIC 415.8-30 uM) S. aureus AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 15.8-40 uM), S. enterica AB 201018
Evidence 3 Activity

Activity

MIC
Antibacterial
15.8-40 µM

Target

P. putida PP

Source & Reference

NA

Other

9 (MIC 415.8-30 uM) S. aureus AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 15.8-40 uM), S. enterica AB 2010185 (MIC 15-40 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
15-40 µM

Target

S. enterica AB 2010185

Source & Reference

NA

Other

AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 15.8-40 uM), S. enterica AB 2010185 (MIC 15-40 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
415.8-30 µM

Target

M. luteus AB2010179

Source & Reference

Antifungipept

Other

Active against Gram+ B. megaterium AB 90008 M. luteus AB2010179 (MIC 415.8-30 uM) S. aureus AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 1
Evidence 6 Activity

Activity

MIC
Antifungal
5.6 µM

Target

Staphylococcus aureus AB 94004

Source & Reference

Antifungipept

Other

Active against Gram+ B. megaterium AB 90008 M. luteus AB2010179 (MIC 415.8-30 uM) S. aureus AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 15.8-40 uM), S. enterica AB 201018
Evidence 7 Activity

Activity

MIC
Antifungal
15.8-40 µM

Target

P. putida PP

Source & Reference

Antifungipept

Other

9 (MIC 415.8-30 uM) S. aureus AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 15.8-40 uM), S. enterica AB 2010185 (MIC 15-40 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
15-40 µM

Target

S. enterica AB 2010185

Source & Reference

Antifungipept

Other

AB 94004 (MIC 5.6 uM) E. coli DH5alpha, P. fluorences PF, P. putida PP (MIC 15.8-40 uM), S. enterica AB 2010185 (MIC 15-40 uM).
Evidence 9 Activity

Activity

2% Hemolysis
Toxicity
0.8 µM
Hemolytic Cytotoxic
2% Hemolysis | 0.8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 10 Activity

Activity

10.6% Hemolysis
Toxicity
1.6 µM
Hemolytic Cytotoxic
10.6% Hemolysis | 1.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 11 Activity

Activity

49.3% Hemolysis
Toxicity
3.2 µM
Hemolytic Cytotoxic
49.3% Hemolysis | 3.2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 12 Activity

Activity

94% Hemolysis
Toxicity
6.4 µM
Hemolytic Cytotoxic
94% Hemolysis | 6.4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Genomic and functional characterization of three new venom peptides from the scorpion Heterometrus spinifer. | Peptides | 2014
Evidence 13 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.