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Peptide record

TPDB10399

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10399
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF pep-lab CAFPdb ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
FLGALFKVASKVLPSVKCAITKKC
Physicochemical Analysis
C119H203N29O28S2
RNDEQHMWY
K
2552.22
10.39
5
0
12
+5
0.78
0.863
113.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.90
5
Residue Composition
number
3
A
0
R
0
N
0
D
2
C
0
E
0
Q
1
G
0
H
1
I
3
L
5
K
0
M
2
F
1
P
2
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 5 M: 0 F: 2 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
24
C119H203N29O28S2
2552.22
10.39
+5
0.78
0.863
Evidence Records 2 records
Evidence 1 Activity

Activity

7% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
7% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Systematic peptide engineering and structural characterization to search for the shortest antimicrobial peptide analogue of gaegurin 5 | J Biol Chem | 2004
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
7 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 7% Hemolysis=100 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Med Chem. 2006 Aug 10 49(16):4886-95.