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Peptide record

TPDB10398

Antibacterial Antifungal Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10398
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete APD_hemolytic Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FLSTLLKVAFKVVPTLFCPITKKC
Physicochemical Analysis
C130H214N28O29S2
RNDEQGHMWY
LK
2697.42
10.17
4
0
12
+4
-0.97
1.075
121.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.63
6
Residue Composition
number
1
A
0
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
1
I
4
L
4
K
0
M
3
F
2
P
1
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 4 M: 0 F: 3 P: 2 S: 1 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
24
C130H214N28O29S2
2697.42
10.17
+4
-0.97
1.075
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
18.75 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram- E. coli ATCC 25922 (MIC 18.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis
Evidence 2 Activity

Activity

MIC
Antibacterial
9.38 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP

Other

Active against Gram- E. coli ATCC 25922 (MIC 18.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and f
Evidence 3 Activity

Activity

MIC
Antibacterial
1.17 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP

Other

gainst Gram- E. coli ATCC 25922 (MIC 18.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and fungi C. albicans ATCC 2002 (MIC 4.7 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
4.7 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP

Other

8.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and fungi C. albicans ATCC 2002 (MIC 4.7 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
4.7 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP

Other

m+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and fungi C. albicans ATCC 2002 (MIC 4.7 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
18.75 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram- E. coli ATCC 25922 (MIC 18.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis
Evidence 7 Activity

Activity

MIC
Antifungal
9.38 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram- E. coli ATCC 25922 (MIC 18.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and f
Evidence 8 Activity

Activity

MIC
Antifungal
1.17 µg/mL

Target

Staphylococcus aureus ATCC 2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

gainst Gram- E. coli ATCC 25922 (MIC 18.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and fungi C. albicans ATCC 2002 (MIC 4.7 ug/ml).
Evidence 9 Activity

Activity

MIC
Antifungal
4.7 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

8.75 ug/ml), B. dysenteriae (MIC 9.38 ug/ml), Gram+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and fungi C. albicans ATCC 2002 (MIC 4.7 ug/ml).
Evidence 10 Activity

Activity

MIC
Antifungal
4.7 µg/mL

Target

Candida albicans ATCC 2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

m+ S. aureus ATCC 2592 (MIC 1.17 ug/ml), B. subtilis ATCC 6633 (MIC 4.7 ug/ml), and fungi C. albicans ATCC 2002 (MIC 4.7 ug/ml).
Evidence 11 Activity

Activity

8% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
8% Hemolysis | 25 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis. | Amino Acids | 2013
Evidence 12 Activity

Activity

25% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
25% Hemolysis | 50 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis. | Amino Acids | 2013
Evidence 13 Activity

Activity

83% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
83% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide diversity in the skin of the torrent frog, Amolops jingdongensis. | Amino Acids | 2013
Evidence 14 Hemolysis

Source & Reference

APD_complete APD_hemolytic PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.