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Peptide record

TPDB10397

Antibacterial Antifungal Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10397
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLGPIIKMATGILPTAICKGLKKC
Physicochemical Analysis
C116H202N28O27S3
RNDEQHSWYV
IK
2517.23
10.17
4
0
11
+4
0.07
0.888
122.08
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.97
4
Residue Composition
number
2
A
0
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
4
I
3
L
4
K
1
M
1
F
2
P
0
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 4 L: 3 K: 4 M: 1 F: 1 P: 2 S: 0 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C116H202N28O27S3
2517.23
10.17
+4
0.07
0.888
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC2592 (MIC 2.5 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (
Evidence 2 Activity

Activity

MIC
Antibacterial
20 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

e against S. aureus ATCC2592 (MIC 2.5 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC2785
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

dbAMP

Other

(MIC 2.5 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albican
Evidence 4 Activity

Activity

MIC
Antibacterial
10 µg/mL

Target

Pseudomonas aeruginosa PA01

Source & Reference

dbAMP

Other

C43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 5 ug/ml).
Evidence 5 Activity

Activity

MIC
Antibacterial
5 µg/mL

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP

Other

ubtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 5 ug/ml).
Evidence 6 Activity

Activity

MIC
Antibacterial
5 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 5 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
2.5 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC2592 (MIC 2.5 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (
Evidence 8 Activity

Activity

MIC
Antifungal
20 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

e against S. aureus ATCC2592 (MIC 2.5 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC2785
Evidence 9 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Escherichia coli ML-35P

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 2.5 ug/ml), S. aureus ATCC43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albican
Evidence 10 Activity

Activity

MIC
Antifungal
10 µg/mL

Target

Pseudomonas aeruginosa PA01

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C43300 (MRSA) (MIC 2.5 ug/ml), B. subtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 5 ug/ml).
Evidence 11 Activity

Activity

MIC
Antifungal
5 µg/mL

Target

Pseudomonas aeruginosa ATCC27853

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ubtilis (MIC 20 ug/ml), E. coli ML-35P (MIC 50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 5 ug/ml).
Evidence 12 Activity

Activity

MIC
Antifungal
5 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

50 ug/ml), P. aeruginosa PA01 (MIC 10 ug/ml), P. aeruginosa ATCC27853 (MIC 5 ug/ml), and C. albicans ATCC2002 (MIC 5 ug/ml).
Evidence 13 Activity

Activity

6% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
6% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Five novel antimicrobial peptides from the Kuhl's wart frog skin secretions, Limnonectes kuhlii. | Mol Biol Rep | 2013