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Peptide record

TPDB10390

Antibacterial Anticancer Antifungal Antiparasitic standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10390
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLPAVIRVAANVLPTAFCAISKKC
Physicochemical Analysis
C117H194N30O28S2
DEQGHMWY
A
2533.13
9.92
3
0
14
+3
-0.74
1.179
122.08
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.93
5
Residue Composition
number
5
A
1
R
1
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
2
L
2
K
0
M
2
F
2
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 5 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 2 M: 0 F: 2 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
24
C117H194N30O28S2
2533.13
9.92
+3
-0.74
1.179
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 6.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
6.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

MIC 6.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC 6.6 ug/ml), and yeast C. albicans (MIC 3.3 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
3.3 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

lled P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC 6.6 ug/ml), and yeast C. albicans (MIC 3.3 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
6.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 6.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
6.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 6.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC 6.6 ug/ml), and yeast C. albicans (MIC 3.3 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
3.3 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

lled P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC 6.6 ug/ml), and yeast C. albicans (MIC 3.3 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
6.6 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 6.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
6.6 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 6.6 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC 6.6 ug/ml), and yeast C. albicans (MIC 3.3 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
3.3 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

lled P. aeruginosa) (MIC 13.2 ug/ml), Gram+ bacteria S. aureus (MIC 6.6 ug/ml), and yeast C. albicans (MIC 3.3 ug/ml). Updated 7/2021