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Peptide record

TPDB10386

Antibacterial Antifungal Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10386
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete APD_hemolytic HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSTLLNVASNVVPTLICKITKKC
Physicochemical Analysis
C118H205N29O32S2
RDEQGHMWY
L
2606.22
9.80
3
0
11
+3
0.51
0.933
137.92
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.80
9
Residue Composition
number
1
A
0
R
2
N
0
D
2
C
0
E
0
Q
0
G
0
H
2
I
4
L
3
K
0
M
1
F
1
P
2
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 4 K: 3 M: 0 F: 1 P: 1 S: 2 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
24
C118H205N29O32S2
2606.22
9.80
+3
0.51
0.933
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
75 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
ive bacteria: R. rhodochrous X15 (IS) (MIC 2.3 uM), B. licheniformis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 75 uM), S. carnosus KHS (IS)(MIC 19 uM), S. aureus ATCC 25923(MIC 19 uM), E.coli ATCC 25922 (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
19 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP

Other

formis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 75 uM), S. carnosus KHS (IS)(MIC 19 uM), S. aureus ATCC 25923(MIC 19 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 1105
Evidence 3 Activity

Activity

MIC
Antibacterial
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

ecalis 981 (MIC 75 uM), S. carnosus KHS (IS)(MIC 19 uM), S. aureus ATCC 25923(MIC 19 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 4 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP DRAMP

Other

0724 (IS)(MIC >150 uM), P. faecalis X29 (IS)(MIC 4.5 uM), S. rubidaea X01 (IS)(MIC 9 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 9 uM). IS: Isolated strain.
Evidence 5 Activity

Activity

MIC
Antifungal
75 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
ive bacteria: R. rhodochrous X15 (IS) (MIC 2.3 uM), B. licheniformis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 75 uM), S. carnosus KHS (IS)(MIC 19 uM), S. aureus ATCC 25923(MIC 19 uM), E.coli ATCC 25922 (MIC
Evidence 6 Activity

Activity

MIC
Antifungal
19 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

formis X39 (IS) (MIC 9 uM), E. faecalis 981 (MIC 75 uM), S. carnosus KHS (IS)(MIC 19 uM), S. aureus ATCC 25923(MIC 19 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 1105
Evidence 7 Activity

Activity

MIC
Antifungal
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ecalis 981 (MIC 75 uM), S. carnosus KHS (IS)(MIC 19 uM), S. aureus ATCC 25923(MIC 19 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 8 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

0724 (IS)(MIC >150 uM), P. faecalis X29 (IS)(MIC 4.5 uM), S. rubidaea X01 (IS)(MIC 9 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 9 uM). IS: Isolated strain.
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
19 µM
Hemolytic Cytotoxic
50% Hemolysis | 19 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis | Peptides | 2012
Evidence 10 Hemolysis

Source & Reference

APD_complete APD_hemolytic HemoPI PD_Hemolysis
APD_complete APD_hemolytic PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.