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Peptide record

TPDB10385

Antibacterial Antifungal Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10385
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLSTALKVAANVVPTLFCKITKKC
Physicochemical Analysis
C120H203N29O30S2
RDEQGHMWY
K
2596.23
10.17
4
0
12
+4
0.35
0.871
113.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.81
7
Residue Composition
number
3
A
0
R
1
N
0
D
2
C
0
E
0
Q
0
G
0
H
1
I
3
L
4
K
0
M
2
F
1
P
1
S
3
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 4 M: 0 F: 2 P: 1 S: 1 T: 3 W: 0 Y: 0 V: 3
Chemical Descriptors
24
C120H203N29O30S2
2596.23
10.17
+4
0.35
0.871
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9 µM

Target

R. rhodochrous X15 IS

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Primarily active against Gram-positive bacteria: bacteria: R. rhodochrous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MI
Evidence 2 Activity

Activity

MIC
Antibacterial
75 µM

Target

B. licheniformis X39 IS

Source & Reference

dbAMP DRAMP

Other

marily active against Gram-positive bacteria: bacteria: R. rhodochrous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC
Evidence 3 Activity

Activity

MIC
Antibacterial
>150 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP DRAMP

Other

acteria: bacteria: R. rhodochrous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (M
Evidence 4 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.carnosus KHS IS

Source & Reference

dbAMP DRAMP

Other

ous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.
Evidence 5 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP DRAMP

Other

formis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pne
Evidence 6 Activity

Activity

MIC
Antibacterial
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

is 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM
Evidence 7 Activity

Activity

MIC
Antibacterial
>150 µM

Target

K.pneumoniae 08040724 IS

Source & Reference

dbAMP DRAMP

Other

0 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231
Evidence 8 Activity

Activity

MIC
Antibacterial
>150 µM

Target

P.faecalis X29 IS

Source & Reference

dbAMP DRAMP

Other

.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223
Evidence 9 Activity

Activity

MIC
Antibacterial
>150 µM

Target

S.rubidaea X01 IS

Source & Reference

dbAMP DRAMP

Other

S (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 75 uM). IS: Isolated stra
Evidence 10 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP DRAMP

Other

40724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 75 uM). IS: Isolated strain.
Evidence 11 Activity

Activity

MIC
Antifungal
9 µM

Target

R. rhodochrous X15 IS

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Primarily active against Gram-positive bacteria: bacteria: R. rhodochrous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MI
Evidence 12 Activity

Activity

MIC
Antifungal
75 µM

Target

B. licheniformis X39 IS

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

marily active against Gram-positive bacteria: bacteria: R. rhodochrous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC
Evidence 13 Activity

Activity

MIC
Antifungal
>150 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

acteria: bacteria: R. rhodochrous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (M
Evidence 14 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.carnosus KHS IS

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ous X15 IS (MIC 9 uM), B. licheniformis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.
Evidence 15 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

formis X39 IS (MIC 75 uM), E.faecalis 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pne
Evidence 16 Activity

Activity

MIC
Antifungal
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

is 981 (MIC >150 uM), S.carnosus KHS IS (MIC >150 uM), S.aureus ATCC 25923 (MIC >150 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM
Evidence 17 Activity

Activity

MIC
Antifungal
>150 µM

Target

K.pneumoniae 08040724 IS

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

0 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231
Evidence 18 Activity

Activity

MIC
Antifungal
>150 µM

Target

P.faecalis X29 IS

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

.aeruginosa CGMCC 1.50 or 11053 IS (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223
Evidence 19 Activity

Activity

MIC
Antifungal
>150 µM

Target

S.rubidaea X01 IS

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

S (MIC >150 uM), K.pneumoniae 08040724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 75 uM). IS: Isolated stra
Evidence 20 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

40724 IS (MIC >150 uM), P.faecalis X29 IS (MIC >150 uM), S.rubidaea X01 IS (MIC >150 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 IS (MIC 75 uM). IS: Isolated strain.
Evidence 21 Activity

Activity

50% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
50% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of diverse antimicrobial peptides in skin secretions of Chungan torrent frog Amolops chunganensis | Peptides | 2012
Evidence 22 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.