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Peptide record

TPDB10380

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10380
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IPWKLPATFRPVERPFSKPFCRKD
Physicochemical Analysis
C138H211N37O31S1
NQGHMY
P
2916.48
10.80
6
2
8
+4
4.72
-0.725
48.75
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
188.58
3
Residue Composition
number
1
A
3
R
0
N
1
D
1
C
1
E
0
Q
0
G
0
H
1
I
1
L
3
K
0
M
3
F
5
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 1 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 3 M: 0 F: 3 P: 5 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
24
C138H211N37O31S1
2916.48
10.80
+4
4.72
-0.725
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
weakly active against Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeas
Evidence 2 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

ainst Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
weakly active against Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeas
Evidence 5 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ainst Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

E.coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
weakly active against Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeas
Evidence 8 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

ainst Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

E.coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
weakly active against Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeas
Evidence 11 Activity

Activity

MIC
Antiviral
100 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

ainst Gram- E.coli (MIC >100 ug/ml), B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
100 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

B. pyocyaneus (P. aeruginosa) (MIC 100 ug/ml), Gram+ S. aureus (MIC 100 ug/ml), and yeast C. albicans (MIC 100 ug/ml). Updated 5/2020 7/2021
Evidence 13 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Extremely abundant antimicrobial peptides existed in the skins of nine kinds of Chinese odorous frogs. | J Proteome Res | 2012
Evidence 14 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:22029824]Non-hemolytic activity against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
J Proteome Res. 2012 Jan 1 11(1):306-319.