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Peptide record

TPDB10373

Antibacterial Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10373
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FLPLLAGLCKITRKCAANFLPKIF
Physicochemical Analysis
C128H209N31O27S2
DEQHMSWYV
L
2678.38
10.32
4
0
13
+4
-2.55
0.950
126.25
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.67
4
Residue Composition
number
3
A
1
R
1
N
0
D
2
C
0
E
0
Q
1
G
0
H
2
I
5
L
3
K
0
M
3
F
2
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 5 K: 3 M: 0 F: 3 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C128H209N31O27S2
2678.38
10.32
+4
-2.55
0.950
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
7 µM
Hemolytic Cytotoxic
100% Hemolysis | 7 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Structure-function studies on the amphibian peptide brevinin 1E: translocating the cationic segment from the C-terminal end to a central position favors selective antibacterial activity. | J Pept Res | 2001
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis