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Peptide record

TPDB10372

Antibacterial Antifungal Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10372
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPLLAGLAANFLPTIICKIARKC
Physicochemical Analysis
C122H204N30O27S2
DEQHMSWYV
L
2587.27
9.92
3
0
14
+3
-2.89
1.258
146.67
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.83
4
Residue Composition
number
4
A
1
R
1
N
0
D
2
C
0
E
0
Q
1
G
0
H
3
I
5
L
2
K
0
M
2
F
2
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 2 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 5 K: 2 M: 0 F: 2 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C122H204N30O27S2
2587.27
9.92
+3
-2.89
1.258
Evidence Records 11 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

N. asteroides 201118

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC 25923, E. faecalis 981, N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), and E. coli ATCC 2
Evidence 2 Activity

Activity

MIC
Antifungal
37.5 µM

Target

N. asteroides 201118

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC 25923, E. faecalis 981, N. asteroides 201118 (MIC 37.5 uM), P.aeruginosa CGMCC 1.50 (inactive), K.pneumoniae 08040724 (inactive), and E. coli ATCC 2
Evidence 3 Activity

Activity

100% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
100% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 4 Activity

Activity

91.5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
91.5% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 5 Activity

Activity

89.3% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
89.3% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 6 Activity

Activity

86.9% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
86.9% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 7 Activity

Activity

85.2% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
85.2% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 8 Activity

Activity

84.9% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
84.9% Hemolysis | 6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 9 Activity

Activity

10.8% Hemolysis
Toxicity
3.1 µM
Hemolytic Cytotoxic
10.8% Hemolysis | 3.1 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 10 Activity

Activity

10.3% Hemolysis
Toxicity
1.6 µM
Hemolytic Cytotoxic
10.3% Hemolysis | 1.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and functional analyses of novel antioxidant peptides and antimicrobial peptides from skin secretions of four East Asian frog species. | Acta Biochim Biophys Sin | 2017
Evidence 11 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.