Back to search

Peptide record

TPDB10361

Bac-ELP122 Bac-ELP43 Bac-ELP63 Bac7 Antibacterial Antifungal Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10361
Bac-ELP122 Bac-ELP43 Bac-ELP63 Bac7
Antibacterial Antifungal Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP CellPPD CPPsite3.0 PerseuCPP
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RRIRPRPPRLPRPRPRPLPFPRPG
Physicochemical Analysis
C133H225N51O25
ANDCEQHKMSTWYV
P
2938.58
13.30
9
0
4
+9
9.24
-1.750
48.75
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
0
K
0
M
1
F
10
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 0 F: 1 P: 10 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C133H225N51O25
2938.58
13.30
+9
9.24
-1.750
Free
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)NCC(=O)O N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 4 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

S2013

Assay & Model

Female athymic nude mice (Ncr-nu/nu)
Female athymic nude mice (Ncr-nu/nu)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Peptide [ELP (Elastin like peptide sequence), Fluorophore (Alexa-Fluor)]
Nucleus
Lower efficiency
In vitro and in vivo
CCCCCCSCSSSCCCSSCSSCCSCC
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

S2013

Assay & Model

Female athymic nude mice (Ncr-nu/nu)
Female athymic nude mice (Ncr-nu/nu)

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L Cationic
Synthetic
Peptide [ELP (Elastin like peptide sequence), Fluorophore (Alexa-Fluor)]
Nucleus
Higher efficiency
In vitro and in vivo
CCCCCCSCSSSCCCSSCSSCCSCC
Evidence 3 Activity

Activity

Cell-penetrating Peptides

Target

S2013

Assay & Model

Female athymic nude mice (Ncr-nu/nu)
Female athymic nude mice (Ncr-nu/nu)

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L Cationic
Synthetic
Peptide [ELP (Elastin like peptide sequence), Fluorophore (Alexa-Fluor)]
Nucleus
Higher efficiency
In vitro and in vivo
CCCCCCSCSSSCCCSSCSSCCSCC
Evidence 4 Activity

Activity

Cell-penetrating Peptides

Target

Ai9 Tdtomato Npcs

Assay & Model

Ai9 or wild-type mice
Ai9 or wild-type mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Natural residues Linear L
SpyCas9 RNPs
>3-fold improvements in genome editing compared to the reference SV40 NLS.
In vitro and in vivo
CCCCTHHHHTTTCCCSSSSCCC
Additional Detail Fields 1 fields
CCCCCCSCSSSCCCSSCSSCCSCC CCCCTHHHHTTTCCCSSSSCCC