Back to search

Peptide record

TPDB10349

Antibacterial Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10349
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GVFRVLRKVTRVVLKVIGKVLKWI
Physicochemical Analysis
C135H236N38O26
ANDCEQHMPSY
V
2807.60
12.72
7
0
14
+7
1.76
0.879
165.83
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
195.90
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
4
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
7
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 7
Chemical Descriptors
24
C135H236N38O26
2807.60
12.72
+7
1.76
0.879
Evidence Records 3 records
Evidence 1 Activity

Activity

45% Hemolysis
Toxicity
4 µM
Hemolytic Cytotoxic
45% Hemolysis | 4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties and membrane-active mechanism of a potential ?-helical antimicrobial derived from cathelicidin PMAP-36. | PLoS One | 2014
Evidence 2 Activity

Activity

90% Hemolysis
Toxicity
16-128 µM
Hemolytic Cytotoxic
90% Hemolysis | 16-128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial properties and membrane-active mechanism of a potential ?-helical antimicrobial derived from cathelicidin PMAP-36. | PLoS One | 2014
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis