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Peptide record

TPDB10338

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10338
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLNAFKKVFQGIHEAIKLINNHVQ
Physicochemical Analysis
C125H200N36O32
RDCMPSTWY
NIK
2719.18
10.32
5
1
11
+2
4.84
-0.050
113.75
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
2
A
0
R
3
N
0
D
0
C
1
E
2
Q
2
G
2
H
3
I
2
L
3
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 0 C: 0 E: 1 Q: 2 G: 2 H: 2 I: 3 L: 2 K: 3 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C125H200N36O32
2719.18
10.32
+2
4.84
-0.050
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
440 µM
Hemolytic Cytotoxic
50% Hemolysis | 440 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of potent, non-toxic antimicrobial agents based upon the structure of the frog skin peptide, pseudin-2. | Regul Pept | 2005