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Peptide record

TPDB10335

Antibacterial Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10335
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GLKALKKVFKGIHKAIKLINKHVK
Physicochemical Analysis
C129H227N37O26
RDCEQMPSTWY
K
2712.45
11.36
10
0
11
+8
6.34
-0.092
130.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
2
H
3
I
3
L
8
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 2 I: 3 L: 3 K: 8 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C129H227N37O26
2712.45
11.36
+8
6.34
-0.092
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
95 µM
Hemolytic Cytotoxic
50% Hemolysis | 95 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of potent, non-toxic antimicrobial agents based upon the structure of the frog skin peptide, pseudin-2. | Regul Pept | 2005
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis