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Peptide record

TPDB10325

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10325
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKLFKKIRGGRLCYCRRRFCVCV
Physicochemical Analysis
C136H224N44O26S4
ANDEQHMPST
R
3019.79
10.97
9
0
9
+9
0.73
-0.208
72.92
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
7240
239.75
5
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
0
E
0
Q
2
G
0
H
1
I
2
L
4
K
0
M
2
F
0
P
0
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
24
C136H224N44O26S4
3019.79
10.97
+9
0.73
-0.208
Evidence Records 1 records
Evidence 1 Activity

Activity

40% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
40% Hemolysis | 256 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Design of hybrid ?-hairpin peptides with enhanced cell specificity and potent anti-inflammatory activity | Biomaterials | 2013