Peptide record

TPDB10324

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10324
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KRFKKFFKKLKNSVKKRAKKFFKK
Physicochemical Analysis
C150H251N43O27
DCEQGHIMPTWY
K
3088.92
12.50
14
0
8
+14
7.74
-1.512
32.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
2
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
12
K
0
M
5
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 12 M: 0 F: 5 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
24
C150H251N43O27
3088.92
12.50
+14
7.74
-1.512
Evidence Records 3 records
Evidence 1 Activity

Activity

0.8% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0.8% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010
Evidence 2 Activity

Activity

1.2% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
1.2% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010
Evidence 3 Activity

Activity

3.0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
3.0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010