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Peptide record

TPDB10323

Antibacterial Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10323
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KRFKKFFKKLKKFVKKGFKKFAKV
Physicochemical Analysis
C153H249N39O25
NDCEQHIMPSTWY
K
3034.91
12.07
13
0
10
+13
5.33
-0.871
44.58
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
12
K
0
M
6
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 12 M: 0 F: 6 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C153H249N39O25
3034.91
12.07
+13
5.33
-0.871
Evidence Records 3 records
Evidence 1 Activity

Activity

0.7% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0.7% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010
Evidence 2 Activity

Activity

1.7% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
1.7% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010
Evidence 3 Activity

Activity

6.0% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
6.0% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationship of king cobra cathelicidin. | Peptides | 2010