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Peptide record

TPDB10312

Antibacterial Antifungal standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10312
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 24-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RFRPPIRRPPIRPPFRPPFRPPVR
Physicochemical Analysis
C142H226N48O25
ANDCEQGHLKMSTWY
P
3005.66
13.25
8
0
6
+8
7.04
-1.267
44.58
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
3
F
10
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 3 P: 10 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
24
C142H226N48O25
3005.66
13.25
+8
7.04
-1.267
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.5 µg/mL

Target

S. enterica serovar Typhimurium 14028s

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
ainst Gram- E. coli O157:H7, 0111, UB1005 rough K-12 strain, ATCC25922 (MIC 2-25 ug/ml), S. enterica serovar Typhimurium 14028s (MIC 0.5 ug/ml), S. enterica serovar Typhimurium MS4252S (phoPQ mutant defensin supersusceptible) (MIC 0
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µg/mL

Target

Staphylococcus epidermidis clinical isolate

Source & Reference

dbAMP

Other

ug/ml), Gram+ S. aureus NCTC 4163 or MRSA R147 or 1056 MRSA (MIC 16-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 16 ug/ml), E. faecalis ATCC 29212 (MIC 32 ug/ml), and yeast C. albicans 105 or 3153A (MIC 32-64 ug/
Evidence 3 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP

Other

r 1056 MRSA (MIC 16-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 16 ug/ml), E. faecalis ATCC 29212 (MIC 32 ug/ml), and yeast C. albicans 105 or 3153A (MIC 32-64 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
32-64 µg/mL

Target

Candida albicans 105 or 3153A

Source & Reference

dbAMP

Other

ermidis clinical isolate (MIC 16 ug/ml), E. faecalis ATCC 29212 (MIC 32 ug/ml), and yeast C. albicans 105 or 3153A (MIC 32-64 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
0.5 µg/mL

Target

S. enterica serovar Typhimurium 14028s

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
ainst Gram- E. coli O157:H7, 0111, UB1005 rough K-12 strain, ATCC25922 (MIC 2-25 ug/ml), S. enterica serovar Typhimurium 14028s (MIC 0.5 ug/ml), S. enterica serovar Typhimurium MS4252S (phoPQ mutant defensin supersusceptible) (MIC 0
Evidence 6 Activity

Activity

MIC
Antifungal
16 µg/mL

Target

Staphylococcus epidermidis clinical isolate

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), Gram+ S. aureus NCTC 4163 or MRSA R147 or 1056 MRSA (MIC 16-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 16 ug/ml), E. faecalis ATCC 29212 (MIC 32 ug/ml), and yeast C. albicans 105 or 3153A (MIC 32-64 ug/
Evidence 7 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Enterococcus faecalis ATCC 29212

Source & Reference

dbAMP CAFPdb Antifungipept

Other

r 1056 MRSA (MIC 16-64 ug/ml or greater), S. epidermidis clinical isolate (MIC 16 ug/ml), E. faecalis ATCC 29212 (MIC 32 ug/ml), and yeast C. albicans 105 or 3153A (MIC 32-64 ug/ml).
Evidence 8 Activity

Activity

MIC
Antifungal
32-64 µg/mL

Target

Candida albicans 105 or 3153A

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ermidis clinical isolate (MIC 16 ug/ml), E. faecalis ATCC 29212 (MIC 32 ug/ml), and yeast C. albicans 105 or 3153A (MIC 32-64 ug/ml).