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Peptide record

TPDB10300

Antibacterial Antifungal Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10300
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLNALKKVFQGIHEAIKKINNHVQ
Physicochemical Analysis
C122H203N37O32
RDCMPSTWY
K
2700.18
10.55
6
1
10
+3
6.96
-0.329
113.75
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
2
A
0
R
3
N
0
D
0
C
1
E
2
Q
2
G
2
H
3
I
2
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 0 C: 0 E: 1 Q: 2 G: 2 H: 2 I: 3 L: 2 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C122H203N37O32
2700.18
10.55
+3
6.96
-0.329
Evidence Records 3 records
Evidence 1 Activity

Activity

0.5% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0.5% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Investigation of cationicity and structure of pseudin-2 analogues for enhanced bacterial selectivity and anti-inflammatory activity. | Sci Rep | 2017
Evidence 2 Activity

Activity

36.38% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
36.38% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018
Evidence 3 Activity

Activity

19% Cytotoxicity
Toxicity
100 µM
Cytotoxic
19% Cytotoxicity | 100 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018