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Peptide record

TPDB10296

Antibacterial Anticancer Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10296
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FFPGIIKVAGAILPTAICAITKRC
Physicochemical Analysis
C117H195N29O27S2
NDEQHMSWY
I
2504.13
9.92
3
0
13
+3
-1.47
1.275
126.25
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.99
4
Residue Composition
number
4
A
1
R
0
N
0
D
2
C
0
E
0
Q
2
G
0
H
5
I
1
L
2
K
0
M
2
F
2
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 1 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 5 L: 1 K: 2 M: 0 F: 2 P: 2 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
24
C117H195N29O27S2
2504.13
9.92
+3
-1.47
1.275
Evidence Records 4 records
Evidence 1 Activity

Activity

60% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
60% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae). | Chem Biol Drug Des | 2017
Evidence 2 Activity

Activity

85% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
85% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae). | Chem Biol Drug Des | 2017
Evidence 3 Activity

Activity

40% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
40% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae). | Chem Biol Drug Des | 2017
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
50% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae). | Chem Biol Drug Des | 2017