TPDB10283

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml),

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cere

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism P. putida

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C.

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 100 µg/mL

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also i

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 75 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

, S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 10 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 11 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 12 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 13 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P

Evidence 14 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml),

Evidence 15 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cere

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism P. putida

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C.

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 100 µg/mL

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also i

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 75 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

, S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Evidence Text

ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiparasitic	DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml),

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cere

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism P. putida

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C.

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 100 µg/mL

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also i

Evidence 28 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 75 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

, S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 29 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 30 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 31 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 2.5 µg/mL

Target

Target Organism M. luteus

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiviral	DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml),

Evidence 32 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 10 µg/mL

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml),

Evidence 33 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 10 µg/mL

Target

Target Organism B. subtilis

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

Active against M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P

Evidence 34 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism Klebsiella pneumoniae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

nst M. luteus (MIC 2.5 ug/ml), S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml),

Evidence 35 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism S. dysentariae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

S. epidermidis (MIC 10 ug/ml), B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cere

Evidence 36 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism P. putida

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

B. subtilis (MIC 10 ug/ml), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C.

Evidence 37 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 100 µg/mL

Target

Target Organism Pseudomonas aeruginosa

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

), K. pneumoniae (MIC 50 ug/ml), S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also i

Evidence 38 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 75 µg/mL

Target

Target Organism Escherichia coli

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

, S. dysentariae (MIC 50 ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of fi

Evidence 39 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism S. cerevisiae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

ug/ml), P. putida (MIC 50 ug/ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans.

Evidence 40 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 50 µg/mL

Target

Target Organism Candida albicans

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

ml), P. aeruginosa (MIC 100 ug/ml), E. coli (MIC 75 ug/ml), S. cerevisiae (MIC 50 ug/ml), C. albicans (MIC 50 ug/ml). Also inhibits the growth of filamentous fungus A. nidulans. It also ruptured protozoan A

Evidence 41 Activity

Activity

Activity Endpoint 1% Hemolysis

Detail Source Activity Toxicity

Activity Measurement 100 µg/mL

Toxicity Type Hemolytic Cytotoxic

Toxicity Raw

1% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Target Cell Human erythrocytes

Source & Reference

Database Source NA

Source Database DBAASP

Reference

Antimicrobial peptides from the skin of a Korean frog, Rana rugosa. | Biochem Biophys Res Commun | 1994

Evidence 42 Activity

Activity

Detail Source Activity Toxicity

Toxicity Type Hemolytic

Toxicity Raw

Hemolytic_activity: [Ref.7999137] It has 0.19% hemolytic activity at 0.1 µg/ml, 0.31% hemolytic activity at 1 µg/ml, 0.78% hemolytic activity at 10 µg/ml, 1.01% hemolytic activity at 100 µg/ml against human red blood cells

Target

Target Cell erythrocytes

Source & Reference

Database Source NA

Source Database DRAMP

Reference

Biochem Biophys Res Commun. 1994 Nov 30 205(1):948-954.