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Peptide record

TPDB10273

Antibacterial Antifungal Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB10273
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
WLNALKKVFQGIHEAIKLINNHVQ
Physicochemical Analysis
C131H209N37O32
RDCMPSTY
NILK
2814.33
10.32
5
1
12
+2
3.55
-0.029
130.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
195.43
5
Residue Composition
number
2
A
0
R
3
N
0
D
0
C
1
E
2
Q
1
G
2
H
3
I
3
L
3
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 3 D: 0 C: 0 E: 1 Q: 2 G: 1 H: 2 I: 3 L: 3 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
24
C131H209N37O32
2814.33
10.32
+2
3.55
-0.029
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
100% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018
Evidence 2 Activity

Activity

98.2% Cytotoxicity
Toxicity
100 µM
Cytotoxic
98.2% Cytotoxicity | 100 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Pse-T2, an antimicrobial peptide with High-Level, Broad-Spectrum Antimicrobial Potency and Skin Biocompatibility against Multidrug-resistant Pseudomonas aeruginosa infection. | Antimicrob Agents Chemother | 2018