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Peptide record

TPDB10254

Antibacterial Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10254
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
KIAKRIWKILRRRLFRRVKKVAG
Physicochemical Analysis
C134H239N47O24
NDCEQHMPSTY
R
2892.67
13.11
11
0
11
+11
4.59
-0.517
118.70
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
190.14
0
Residue Composition
number
2
A
6
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
5
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
23
C134H239N47O24
2892.67
13.11
+11
4.59
-0.517
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
3.91 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 3.91 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel, rationally designed, hybrid antimicrobial peptide, inspired by cathelicidin and aurein, exhibits membrane-active mechanisms against Pseudomonas aeruginosa. | Sci Rep | 2020
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A novel, rationally designed, hybrid antimicrobial peptide, inspired by cathelicidin and aurein, exhibits membrane-active mechanisms against Pseudomonas aeruginosa. | Sci Rep | 2020
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis