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Peptide record

TPDB10248

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10248
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KFFKFFKFFKGTNLYMLPKWDIP
Physicochemical Analysis
C151H212N30O29S1
ARCEQHSV
F
2943.59
10.47
5
1
12
+4
-3.58
-0.096
50.87
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
237.47
3
Residue Composition
number
0
A
0
R
1
N
1
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
5
K
1
M
6
F
2
P
0
S
1
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 5 M: 1 F: 6 P: 2 S: 0 T: 1 W: 1 Y: 1 V: 0
Chemical Descriptors
23
C151H212N30O29S1
2943.59
10.47
+4
-3.58
-0.096
Evidence Records 1 records
Evidence 1 Activity

Activity

0.7±0.2% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
0.7±0.2% Hemolysis | 64 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Triple-targeting Gram-negative selective antimicrobial peptides capable of disrupting the cell membrane and lipid A biosynthesis | RSC Adv | 2016