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Peptide record

TPDB10244

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10244
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic Hemolytic2
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLFGKSSVVGRKYYVDLAGCAKA
Physicochemical Analysis
C108H173N29O30S1
NEQHIMPTW
G
2389.80
9.90
4
1
11
+3
0.64
0.235
84.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
2980
124.70
5
Residue Composition
number
3
A
1
R
0
N
1
D
1
C
0
E
0
Q
4
G
0
H
0
I
2
L
3
K
0
M
1
F
0
P
2
S
0
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 2 K: 3 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 2 V: 3
Chemical Descriptors
23
C108H173N29O30S1
2389.80
9.90
+3
0.64
0.235
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
6.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 3 Activity

Activity

MIC
Antibacterial
6.3 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 4 Activity

Activity

MIC
Antibacterial
3.2 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

nst E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 5 Activity

Activity

MIC
Antifungal
12.6 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
6.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 7 Activity

Activity

MIC
Antifungal
6.3 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 8 Activity

Activity

MIC
Antifungal
3.2 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

nst E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 9 Activity

Activity

MIC
Antiparasitic
12.6 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiparasitic
6.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 11 Activity

Activity

MIC
Antiparasitic
6.3 µg/mL

Target

B. subtilis

Source & Reference

NA

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 12 Activity

Activity

MIC
Antiparasitic
3.2 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

nst E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 13 Activity

Activity

MIC
Antiviral
12.6 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml).
Evidence 14 Activity

Activity

MIC
Antiviral
6.3 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 15 Activity

Activity

MIC
Antiviral
6.3 µg/mL

Target

B. subtilis

Source & Reference

NA

Other

active against E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 16 Activity

Activity

MIC
Antiviral
3.2 µg/mL

Target

Candida albicans

Source & Reference

NA

Other

nst E. coli (MIC 12.6 ug/ml), S. aureus (MIC 6.3 ug/ml), B. subtilis (MIC 6.3 ug/ml), and C. albicans (MIC 3.2 ug/ml). Also histamine release.
Evidence 17 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.