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Peptide record

TPDB10243

Antibacterial Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10243
Antibacterial Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antiparasitic, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, PD_Hemolysis, and other sources, with an available 3D structural model.
Sequence
LIGLVSKGTSVLVKTVSKKVLKQ
Physicochemical Analysis
C111H205N29O30
ARNDCEHMFPWY
KV
2426.03
11.12
5
0
10
+5
4.02
0.570
147.83
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
6
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
1
I
4
L
5
K
0
M
0
F
0
P
3
S
2
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 1 L: 4 K: 5 M: 0 F: 0 P: 0 S: 3 T: 2 W: 0 Y: 0 V: 5
Chemical Descriptors
23
C111H205N29O30
2426.03
11.12
+5
4.02
0.570
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Killing
Toxicity
>15 µM
Cytotoxic
50% Killing | >15 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
>15 µM
Hemolytic Cytotoxic
50% Hemolysis | >15 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Delta-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities | Angew Chem Int Ed Engl | 2017
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis