Back to search

Peptide record

TPDB10238

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10238
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIGKFIHAVKKWGKTFIGEIAKS
Physicochemical Analysis
C120H191N31O28
RNDCQLMPY
K
2516.03
10.71
6
1
10
+4
2.62
0.052
89.13
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
218.60
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
4
G
1
H
4
I
0
L
5
K
0
M
2
F
0
P
1
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 4 L: 0 K: 5 M: 0 F: 2 P: 0 S: 1 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C120H191N31O28
2516.03
10.71
+4
2.62
0.052
Evidence Records 2 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
334.0 µM
Hemolytic Cytotoxic
25% Hemolysis | 334.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum. | Antimicrob Agents Chemother | 2009
Evidence 2 Activity

Activity

25% Hemolysis
Toxicity
>400.0 µM
Hemolytic Cytotoxic
25% Hemolysis | >400.0 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum. | Antimicrob Agents Chemother | 2009