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Peptide record

TPDB10237

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10237
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RIIDLLARVRRPQKPKFVTVWVR
Physicochemical Analysis
C132H224N42O28
NCEGHMSY
R
2847.50
12.58
7
1
11
+6
4.27
-0.178
122.61
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
193.15
2
Residue Composition
number
1
A
5
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
2
I
2
L
2
K
0
M
1
F
2
P
0
S
1
T
1
W
0
Y
4
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 2 K: 2 M: 0 F: 1 P: 2 S: 0 T: 1 W: 1 Y: 0 V: 4
Chemical Descriptors
23
C132H224N42O28
2847.50
12.58
+6
4.27
-0.178
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of tryptophan residues of porcine myeloid antibacterial peptide PMAP-23 on antibiotic activity. | Biochem Biophys Res Commun | 1999
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.10527878] 0% hemolysis at 100 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochem Biophys Res Commun. 1999 Oct 14 264(1):281-6.