Back to search

Peptide record

TPDB10234

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10234
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLKGLLGKALKGIGKHIGKAQGC
Physicochemical Analysis
C100H179N31O25S1
RNDEMFPSTWYV
G
2247.77
10.71
6
0
8
+5
3.12
0.057
110.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
1
C
0
E
1
Q
7
G
1
H
2
I
4
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 7 H: 1 I: 2 L: 4 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C100H179N31O25S1
2247.77
10.71
+5
3.12
0.057
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>500 µM
Hemolytic Cytotoxic
50% Hemolysis | >500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences. | Biochim Biophys Acta | 2013
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
20±4 µM
Hemolytic Cytotoxic
50% Hemolysis | 20±4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Selective antimicrobial activity and mode of action of adepantins, glycine-rich peptide antibiotics based on anuran antimicrobial peptide sequences. | Biochim Biophys Acta | 2013