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Peptide record

TPDB10228

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10228
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLLSGILGAGKHIVCGLTGCAKA
Physicochemical Analysis
C93H163N27O26S2
RNDEQMFPWY
G
2139.60
9.11
3
0
10
+2
-0.51
1.039
127.39
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
5.84
4
Residue Composition
number
3
A
0
R
0
N
0
D
2
C
0
E
0
Q
6
G
1
H
2
I
4
L
2
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 6 H: 1 I: 2 L: 4 K: 2 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C93H163N27O26S2
2139.60
9.11
+2
-0.51
1.039
Evidence Records 14 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
9.375 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP

Other

active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
18.750 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP

Other

(MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 4 Activity

Activity

MIC
Antifungal
37.5 µg/mL

Target

B. dysenteriae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
9.375 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 6 Activity

Activity

MIC
Antifungal
18.750 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

(MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 7 Activity

Activity

MIC
Antiparasitic
37.5 µg/mL

Target

B. dysenteriae

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 8 Activity

Activity

MIC
Antiparasitic
9.375 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

DRAMP

Other

active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 9 Activity

Activity

MIC
Antiparasitic
18.750 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

DRAMP

Other

(MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 10 Activity

Activity

MIC
Antiviral
37.5 µg/mL

Target

B. dysenteriae

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 11 Activity

Activity

MIC
Antiviral
9.375 µg/mL

Target

Staphylococcus aureus ATCC2592

Source & Reference

DRAMP

Other

active against E.coli ATCC25922 (MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 12 Activity

Activity

MIC
Antiviral
18.750 µg/mL

Target

Candida albicans ATCC2002

Source & Reference

DRAMP

Other

(MIC > 100 ug/ml), B. dysenteriae (MIC 37.5 ug/ml), S. aureus ATCC2592 (MIC 9.375 ug/ml), C. albicans ATCC2002 (MIC 18.750 ug/ml).
Evidence 13 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
A novel antimicrobial peptide from amphibian skin secretions of Odorrana grahami. | Peptides | 2008
Evidence 14 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:18282640] It has little hemolytic activity at 100 µg/ml against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Peptides. 2008 Apr 29(4):529-535.