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Peptide record

TPDB10212

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10212
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
GIGKFLHSAKKFGKAFVAEIMNS
Physicochemical Analysis
C115H182N30O29S1
RDCQPTWY
K
2480.95
10.55
5
1
11
+3
2.41
0.178
76.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
3
A
0
R
1
N
0
D
0
C
1
E
0
Q
3
G
1
H
2
I
1
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 1 I: 2 L: 1 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C115H182N30O29S1
2480.95
10.55
+3
2.41
0.178
Evidence Records 3 records
Evidence 1 Activity

Activity

29% Hemolysis
Toxicity
8 µg/mL
Hemolytic Cytotoxic
29% Hemolysis | 8 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015
Evidence 2 Activity

Activity

88% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
88% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa. | J Pept Sci | 2015
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis