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Peptide record

TPDB10197

Antibacterial Antifungal Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10197
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GIKEFAHSLGKFGKAFVGGILNQ
Physicochemical Analysis
C113H176N30O29
RDCMPTWY
G
2418.82
10.32
4
1
10
+2
1.73
0.200
89.13
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
1
E
1
Q
5
G
1
H
2
I
2
L
3
K
0
M
3
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 1 G: 5 H: 1 I: 2 L: 2 K: 3 M: 0 F: 3 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C113H176N30O29
2418.82
10.32
+2
1.73
0.200
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
50% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human oral fibroblasts

Target

Human oral fibroblasts

Source & Reference

NA
DBAASP
Antimicrobial and immunomodulatory properties of PGLa-AM1, CPF-AM1, and magainin-AM1: potent activity against oral pathogens. | Regul Pept | 2014
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis