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Peptide record

TPDB10191

Antibacterial Antifungal Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10191
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FIHHIIGGLFSVGKHIHGLIHGH
Physicochemical Analysis
C120H180N36O25
ARNDCEQMPTWY
H
2526.98
10.10
7
0
10
+2
2.07
0.609
131.30
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
5
G
6
H
5
I
2
L
1
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 6 I: 5 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C120H180N36O25
2526.98
10.10
+2
2.07
0.609
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus (MIC 5 uM), B. subtilis (MIC 3 uM), P. aeruginosa (35 uM), E. coli (6.7 uM), C. albicans (20 uM). Up
Evidence 2 Activity

Activity

MIC
Antibacterial
3 µM

Target

B. subtilis

Source & Reference

dbAMP

Other

Active against S. aureus (MIC 5 uM), B. subtilis (MIC 3 uM), P. aeruginosa (35 uM), E. coli (6.7 uM), C. albicans (20 uM). Updated 5/2017.
Evidence 3 Activity

Activity

MIC
Antifungal
5 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus (MIC 5 uM), B. subtilis (MIC 3 uM), P. aeruginosa (35 uM), E. coli (6.7 uM), C. albicans (20 uM). Up
Evidence 4 Activity

Activity

MIC
Antifungal
3 µM

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against S. aureus (MIC 5 uM), B. subtilis (MIC 3 uM), P. aeruginosa (35 uM), E. coli (6.7 uM), C. albicans (20 uM). Updated 5/2017.
Evidence 5 Activity

Activity

0% Hemolysis
Toxicity
55 µM
Hemolytic Cytotoxic
0% Hemolysis | 55 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cloning and functional characterization of three novel antimicrobial peptides from tilapia (Oreochromis niloticus). | Aquaculture | 2013
Evidence 6 Activity

Activity

23% Hemolysis
Toxicity
55 µM
Hemolytic Cytotoxic
23% Hemolysis | 55 | µM | target cell: Tilapia erythrocytes

Target

Tilapia erythrocytes

Source & Reference

NA
DBAASP
Cloning and functional characterization of three novel antimicrobial peptides from tilapia (Oreochromis niloticus). | Aquaculture | 2013