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Peptide record

TPDB10185

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10185
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb APD_complete HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGKFLHSAGKFGKAFIGEIMKS
Physicochemical Analysis
C113H179N29O28S1
RNDCQPTWYV
G
2423.90
10.55
5
1
10
+3
1.80
0.230
76.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
5
G
1
H
3
I
1
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 5 H: 1 I: 3 L: 1 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C113H179N29O28S1
2423.90
10.55
+3
1.80
0.230
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
50 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC1 2.5 uM), S. aureus (MIC 50 uM), and C. albicans (MIC 25 uM). Hemolytic HL50=180.
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µM

Target

Candida albicans

Source & Reference

dbAMP

Other

Active against E. coli (MIC1 2.5 uM), S. aureus (MIC 50 uM), and C. albicans (MIC 25 uM). Hemolytic HL50=180.
Evidence 3 Activity

Activity

MIC
Antifungal
50 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC1 2.5 uM), S. aureus (MIC 50 uM), and C. albicans (MIC 25 uM). Hemolytic HL50=180.
Evidence 4 Activity

Activity

MIC
Antifungal
25 µM

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against E. coli (MIC1 2.5 uM), S. aureus (MIC 50 uM), and C. albicans (MIC 25 uM). Hemolytic HL50=180.
Evidence 5 Activity

Activity

MIC
Antiparasitic
50 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC1 2.5 uM), S. aureus (MIC 50 uM), and C. albicans (MIC 25 uM). Hemolytic HL50=180.
Evidence 6 Activity

Activity

MIC
Antiparasitic
25 µM

Target

Candida albicans

Source & Reference

NA

Other

Active against E. coli (MIC1 2.5 uM), S. aureus (MIC 50 uM), and C. albicans (MIC 25 uM). Hemolytic HL50=180.
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
180 µM
Hemolytic Cytotoxic
50% Hemolysis | 180 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptidomic analysis of skin secretions demonstrates that the allopatric populations of Xenopus muelleri (Pipidae) are not conspecific. | Peptides | 2011
Evidence 8 Hemolysis

Source & Reference

APD_complete HemoPI PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.