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Peptide record

TPDB10179

Antibacterial Antifungal Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10179
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
VEVQVRDKGKGIYGLSPLRQPAP
Physicochemical Analysis
C112H187N33O32
NCHMFTW
GPV
2507.92
10.19
4
2
8
+2
7.19
-0.539
93.04
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
59.41
4
Residue Composition
number
1
A
2
R
0
N
1
D
0
C
1
E
2
Q
3
G
0
H
1
I
2
L
2
K
0
M
0
F
3
P
1
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 1 C: 0 E: 1 Q: 2 G: 3 H: 0 I: 1 L: 2 K: 2 M: 0 F: 0 P: 3 S: 1 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
23
C112H187N33O32
2507.92
10.19
+2
7.19
-0.539
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 2 Activity

Activity

(3.5±1.6)% degranulation
Toxicity
50 µg/mL
Cytotoxic
(3.5±1.6)% degranulation | 50 | µg/mL | target cell: Human mast cells

Target

Human mast cells

Source & Reference

NA
DBAASP
Anti-infection peptidomics of amphibian skin. | Mol Cell Proteomics | 2007
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:17272268]Non-hemolytic activity against rabbit red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Mol Cell Proteomics. 2007 May 6(5):882-894.