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Peptide record

TPDB10170

Antibacterial Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10170
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GIGKFLHKVKSFGKSWIGEIMNS
Physicochemical Analysis
C119H187N31O30S1
ARDCQPTY
GK
2564.04
10.55
5
1
9
+3
2.03
-0.074
80.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
214.50
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
3
I
1
L
4
K
1
M
2
F
0
P
3
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 3 L: 1 K: 4 M: 1 F: 2 P: 0 S: 3 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C119H187N31O30S1
2564.04
10.55
+3
2.03
-0.074
Evidence Records 2 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
25% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of the angle subtended by the positively charged helix face on the membrane activity of amphipathic, antibacterial peptides. | Biochemistry | 1997
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis