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Peptide record

TPDB10165

Antibacterial Antifungal Antiviral Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10165
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GEGFLGMLLHGVGHAIHGLIHGK
Physicochemical Analysis
C107H168N32O26S1
RNDCQPSTWY
G
2350.77
8.12
5
1
10
+0
2.60
0.517
118.70
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
7
G
4
H
2
I
4
L
1
K
1
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 7 H: 4 I: 2 L: 4 K: 1 M: 1 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C107H168N32O26S1
2350.77
8.12
+0
2.60
0.517
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.9-3.9 µM

Target

Escherichia coli JM109

Source & Reference

NA

Other

(MIC < 0.9 uM), V. harveyi ATCC14126 (MIC < 0.9 uM), V. ordalii KCCM41669 (MIC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V.
Evidence 2 Activity

Activity

MIC
Antibacterial
0.9-1.9 µM

Target

V. alginolyticus KCCM2928

Source & Reference

NA

Other

4126 (MIC < 0.9 uM), V. ordalii KCCM41669 (MIC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inact
Evidence 3 Activity

Activity

MIC
Antibacterial
1.9 µM

Target

V. campbellii KCCM40684

Source & Reference

NA

Other

IC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
3.9-7.8 µM

Target

V. vulnificus KCTC2982

Source & Reference

NA

Other

M), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
250-500 µM

Target

E.tarda

Source & Reference

NA

Other

campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 6 Activity

Activity

MIC
Antifungal
1.9-3.9 µM

Target

Escherichia coli JM109

Source & Reference

Antifungipept

Other

(MIC < 0.9 uM), V. harveyi ATCC14126 (MIC < 0.9 uM), V. ordalii KCCM41669 (MIC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V.
Evidence 7 Activity

Activity

MIC
Antifungal
0.9-1.9 µM

Target

V. alginolyticus KCCM2928

Source & Reference

Antifungipept

Other

4126 (MIC < 0.9 uM), V. ordalii KCCM41669 (MIC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inact
Evidence 8 Activity

Activity

MIC
Antifungal
1.9 µM

Target

V. campbellii KCCM40684

Source & Reference

Antifungipept

Other

IC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 9 Activity

Activity

MIC
Antifungal
3.9-7.8 µM

Target

V. vulnificus KCTC2982

Source & Reference

Antifungipept

Other

M), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
250-500 µM

Target

E.tarda

Source & Reference

Antifungipept

Other

campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 11 Activity

Activity

MIC
Antiviral
1.9-3.9 µM

Target

Escherichia coli JM109

Source & Reference

NA

Other

(MIC < 0.9 uM), V. harveyi ATCC14126 (MIC < 0.9 uM), V. ordalii KCCM41669 (MIC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V.
Evidence 12 Activity

Activity

MIC
Antiviral
0.9-1.9 µM

Target

V. alginolyticus KCCM2928

Source & Reference

NA

Other

4126 (MIC < 0.9 uM), V. ordalii KCCM41669 (MIC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inact
Evidence 13 Activity

Activity

MIC
Antiviral
1.9 µM

Target

V. campbellii KCCM40684

Source & Reference

NA

Other

IC < 0.9 uM), E. coli JM109 (MIC 1.9-3.9 uM), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 14 Activity

Activity

MIC
Antiviral
3.9-7.8 µM

Target

V. vulnificus KCTC2982

Source & Reference

NA

Other

M), V. alginolyticus KCCM2928 (MIC 0.9-1.9 uM), V. campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 15 Activity

Activity

MIC
Antiviral
250-500 µM

Target

E.tarda

Source & Reference

NA

Other

campbellii KCCM40684 (MIC 1.9 uM), and V. vulnificus KCTC2982 (MIC 3.9-7.8 uM). Inactive: E.tarda (MIC 250-500 uM).
Evidence 16 Activity

Activity

29% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
29% Hemolysis | 250 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Piscidin: Antimicrobial peptide of rock bream, Oplegnathus fasciatus. | Fish Shellfish Immunol | 2016
Evidence 17 Activity

Activity

13% Hemolysis
Toxicity
125 µM
Hemolytic Cytotoxic
13% Hemolysis | 125 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Piscidin: Antimicrobial peptide of rock bream, Oplegnathus fasciatus. | Fish Shellfish Immunol | 2016
Evidence 18 Activity

Activity

0% Hemolysis
Toxicity
63 µM
Hemolytic Cytotoxic
0% Hemolysis | 63 | µM | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Piscidin: Antimicrobial peptide of rock bream, Oplegnathus fasciatus. | Fish Shellfish Immunol | 2016