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Peptide record

TPDB10162

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10162
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GILDTLKQFAKGVGKWLVKGAAQ
Physicochemical Analysis
C113H186N30O29
RNCEHMPSY
GK
2428.90
10.55
4
1
11
+3
1.19
0.139
106.09
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
226.44
3
Residue Composition
number
3
A
0
R
0
N
1
D
0
C
0
E
2
Q
4
G
0
H
1
I
3
L
4
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 2 G: 4 H: 0 I: 1 L: 3 K: 4 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
23
C113H186N30O29
2428.90
10.55
+3
1.19
0.139
Evidence Records 3 records
Evidence 1 Activity

Activity

0.02% Hemolysis
Toxicity
10 µg/mL
Hemolytic Cytotoxic
0.02% Hemolysis | 10 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4. | Eur J Biochem | 2002
Evidence 2 Activity

Activity

0.38% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0.38% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of a tryptophanyl substitution on the structure and antimicrobial activity of C-terminally truncated gaegurin 4. | Eur J Biochem | 2002
Evidence 3 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.12199716] 0.02% hemolytic activity at 10 µg/mL, 0.38% hemolytic activity at 100 µg/mL against human red blood cells.

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur J Biochem. 2002 Sep 269(17):4367-4374.