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Peptide record

TPDB10152

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10152
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FKRFIGSVKHGIGHLVHHIGVAL
Physicochemical Analysis
C119H188N36O25
NDCEQMPTWY
GH
2523.03
11.64
7
0
11
+3
2.53
0.591
126.96
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
4
G
4
H
3
I
2
L
2
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 4 I: 3 L: 2 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
23
C119H188N36O25
2523.03
11.64
+3
2.53
0.591
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
Toxicity
188 µM
Cytotoxic
EC50 | 188 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
>400 µM
Hemolytic Cytotoxic
10% Hemolysis | >400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018