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Peptide record

TPDB10144

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10144
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLWSKIKEVGKEAAKAAAKAAGK
Physicochemical Analysis
C104H178N30O29
RNDCQHMFPTY
A
2312.74
10.54
6
2
11
+4
6.30
-0.357
76.96
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
237.81
1
Residue Composition
number
7
A
0
R
0
N
0
D
0
C
2
E
0
Q
3
G
0
H
1
I
1
L
6
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 7 R: 0 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 3 H: 0 I: 1 L: 1 K: 6 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C104H178N30O29
2312.74
10.54
+4
6.30
-0.357
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
50 µM
Cytotoxic
0% Cytotoxicity | 50 | µM | target cell: Chinese hamster ovary cells CHO

Target

Chinese hamster ovary cells CHO

Source & Reference

NA
DBAASP
Mechanism of antibacterial action of dermaseptin B2: interplay between helix-hinge-helix structure and membrane curvature strain. | Biochemistry | 2009