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Peptide record

TPDB10142

Antibacterial Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10142
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
GLKEVLHSTKKFAKGFITGLTGQ
Physicochemical Analysis
C113H186N30O31
RNDCMPWY
GK
2460.90
10.55
5
1
8
+3
3.76
-0.122
84.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
4
G
1
H
1
I
3
L
4
K
0
M
2
F
0
P
1
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 4 H: 1 I: 1 L: 3 K: 4 M: 0 F: 2 P: 0 S: 1 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C113H186N30O31
2460.90
10.55
+3
3.76
-0.122
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>160 µM
Hemolytic Cytotoxic
50% Hemolysis | >160 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Host-defense peptides in skin secretions of the tetraploid frog Silurana epitropicalis with potent activity against methicillin-resistant Staphylococcus aureus (MRSA). | Peptides | 2012
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis