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Peptide record

TPDB10141

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10141
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIGRFLHSARRFGRAFVGEIMNS
Physicochemical Analysis
C114H180N38O29S1
DCQKPTWY
RG
2578.98
12.40
5
1
10
+3
1.87
-0.022
72.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
1
E
0
Q
4
G
1
H
2
I
1
L
0
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 1 I: 2 L: 1 K: 0 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C114H180N38O29S1
2578.98
12.40
+3
1.87
-0.022
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
251.9±48.2 µM
Hemolytic Cytotoxic
50% Hemolysis | 251.9±48.2 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity. | PLoS One | 2016