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Peptide record

TPDB10136

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10136
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FLPKTLRKFFARIRGGRAAVLNA
Physicochemical Analysis
C121H200N38O26
DCEQHMSWY
AR
2603.16
12.88
6
0
12
+6
0.26
0.143
97.83
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
4
A
4
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
3
L
2
K
0
M
3
F
1
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 3 K: 2 M: 0 F: 3 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C121H200N38O26
2603.16
12.88
+6
0.26
0.143
Evidence Records 2 records
Evidence 1 Activity

Activity

18% Killing
Toxicity
10 µg/mL
Cytotoxic
18% Killing | 10 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Antimicrobial peptide-loaded liquid crystalline precursor bioadhesive system for the prevention of dental caries. | Int J Nanomedicine | 2018
Evidence 2 Activity

Activity

>95% Killing
Toxicity
1000 µg/mL
Cytotoxic
>95% Killing | 1000 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Antimicrobial peptide-loaded liquid crystalline precursor bioadhesive system for the prevention of dental caries. | Int J Nanomedicine | 2018