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Peptide record

TPDB10134

Antibacterial Antifungal Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10134
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KWKLFKKIFKCWRWQWRWKKLGA
Physicochemical Analysis
C158H232N42O25S1
NDEHMPSTYV
K
3151.91
11.76
9
0
11
+9
-4.21
-0.987
55.22
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
27500
872.49
2
Residue Composition
number
1
A
2
R
0
N
0
D
1
C
0
E
1
Q
1
G
0
H
1
I
2
L
7
K
0
M
2
F
0
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 2 K: 7 M: 0 F: 2 P: 0 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
23
C158H232N42O25S1
3151.91
11.76
+9
-4.21
-0.987
Evidence Records 3 records
Evidence 1 Activity

Activity

9% Hemolysis
Toxicity
3.13 µM
Hemolytic Cytotoxic
9% Hemolysis | 3.13 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Design and characterization of novel hybrid peptides from LFB15(W4,10), HP(2-20), and cecropin A based on structure parameters by computer-aided method. | Appl Microbiol Biotechnol | 2009
Evidence 2 Activity

Activity

91% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
91% Hemolysis | 200 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Design and characterization of novel hybrid peptides from LFB15(W4,10), HP(2-20), and cecropin A based on structure parameters by computer-aided method. | Appl Microbiol Biotechnol | 2009
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis