Back to search

Peptide record

TPDB10133

Antibacterial Anticancer Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10133
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KISKKIMRTFLRRISKDILTGKK
Physicochemical Analysis
C124H226N38O30S1
ANCEQHPWYV
K
2761.46
12.18
9
1
8
+8
6.43
-0.587
101.74
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
0
A
3
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
4
I
2
L
6
K
1
M
1
F
0
P
2
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 4 L: 2 K: 6 M: 1 F: 1 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C124H226N38O30S1
2761.46
12.18
+8
6.43
-0.587
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rationale for the design of shortened derivatives of the NK-lysin-derived antimicrobial peptide NK-2 with improved activity against Gram-negative pathogens. | J Biol Chem | 2007
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
5 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: <5% Hemolysis=100 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2007 May 18 282(20):14719-28.