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Peptide record

TPDB10128

Antibacterial Hemolysis Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10128
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, HemoPI, and other sources, with an available 3D structural model.
Sequence
RVKRVWPLVIRTVIAGYNLYRAI
Physicochemical Analysis
C130H214N38O28
DCEQHMFS
RV
2757.37
11.96
5
0
14
+5
-0.59
0.430
143.91
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8480
307.54
4
Residue Composition
number
2
A
4
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
1
K
0
M
0
F
1
P
0
S
1
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 1 M: 0 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 2 V: 4
Chemical Descriptors
23
C130H214N38O28
2757.37
11.96
+5
-0.59
0.430
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
38 µM
Hemolytic Cytotoxic
50% Hemolysis | 38 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006
Evidence 2 Activity

Activity

50% Cell death
Toxicity
40 µM
Cytotoxic
50% Cell death | 40 | µM | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken | FASEB J | 2006
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis