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Peptide record

TPDB10114

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10114
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GIGHFLHKVKSFGKSWIGEIMNS
Physicochemical Analysis
C119H182N32O30S1
ARDCQPTY
G
2573.01
10.32
5
1
9
+2
2.00
-0.043
80.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
213.76
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
1
E
0
Q
4
G
2
H
3
I
1
L
3
K
1
M
2
F
0
P
3
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 4 H: 2 I: 3 L: 1 K: 3 M: 1 F: 2 P: 0 S: 3 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C119H182N32O30S1
2573.01
10.32
+2
2.00
-0.043
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
82 µM
Hemolytic Cytotoxic
50% Hemolysis | 82 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hydrophobicity, hydrophobic moment and angle subtended by charged residues modulate antibacterial and haemolytic activity of amphipathic helical peptides | FEBS Lett | 1997