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Peptide record

TPDB10113

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10113
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GICKFLHSAKKFGKAFVGEIMNS
Physicochemical Analysis
C115H182N30O29S2
RDQPTWY
K
2513.01
10.17
5
1
10
+3
2.34
0.209
72.17
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
2
A
0
R
1
N
0
D
1
C
1
E
0
Q
3
G
1
H
2
I
1
L
4
K
1
M
3
F
0
P
2
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 1 E: 1 Q: 0 G: 3 H: 1 I: 2 L: 1 K: 4 M: 1 F: 3 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
23
C115H182N30O29S2
2513.01
10.17
+3
2.34
0.209
Evidence Records 1 records
Evidence 1 Activity

Activity

9% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
9% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Lentivirus-derived antimicrobial peptides: increased potency by sequence engineering and dimerization. | J Antimicrob Chemother | 1999