Back to search

Peptide record

TPDB10111

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB10111
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FKRFKGSVKHGKGHLVHHIGVAL
Physicochemical Analysis
C119H190N38O25
NDCEQMPTWY
GHK
2553.06
11.80
9
0
9
+5
5.13
-0.139
93.04
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
4
G
4
H
1
I
2
L
4
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 4 I: 1 L: 2 K: 4 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
23
C119H190N38O25
2553.06
11.80
+5
5.13
-0.139
Evidence Records 3 records
Evidence 1 Activity

Activity

EC50
Toxicity
>400 µM
Cytotoxic
EC50 | >400 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
269 µM
Hemolytic Cytotoxic
10% Hemolysis | 269 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018
Evidence 3 Activity

Activity

50% hemolysis
Toxicity
>400 µM
Hemolytic Cytotoxic
50% hemolysis | >400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
New antimicrobial peptide kills drug-resistant pathogens without detectable resistance | Oncotarget | 2018