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Peptide record

TPDB10109

Antibacterial Antifungal Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB10109
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP ToxinPred 3.0
standard
No
A 23-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
IIGLVSKGTCVLVKTVCKKVLKQ
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C111H205N29O28S2
ARNDEHMFPWY
KV
2458.15
10.39
5
0
10
+5
-0.32
0.887
147.83
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
125
0.05
6
Residue Composition
number
0
A
0
R
0
N
0
D
2
C
0
E
1
Q
2
G
0
H
2
I
3
L
5
K
0
M
0
F
0
P
1
S
2
T
0
W
0
Y
5
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 3 K: 5 M: 0 F: 0 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 5
Chemical Descriptors
23 reviewed residue count
C111H205N29O28S2 sequence-only estimate (linear, free termini)
2458.15 sequence-only estimate (linear, free termini)
10.39 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
-0.32 sequence-only estimate (linear, free termini)
0.887 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular cloning and biological characterization of novel antimicrobial peptides, pilosulin 3 and pilosulin 4, from a species of the Australian ant genus Myrmecia. | Arch Biochem Biophys | 2004